From Matthew Perry to Hayden Panettiere: Every Celeb We Lost to Substance Abuse in the Last 5 Years

Hollywood has been writing this obituary for a very long time. Substance abuse issues have claimed the lives of celebs like Heath Ledger, Amy Winehouse, Whitney Houston, Philip Seymour Hoffman, Prince, Michael Jackson, and most recently, Matthew Perry and Hayden Panettiere.

Every few years, another name is added, the industry grieves loudly for a week, and very little changes. On August 16, 2026, Panettiere was found unresponsive in a South Carolina apartment at 36. Her death remains under investigation.

The past five years alone have taken pop stars, child actors, rock drummers, and sitcom legends. Most were young. Most had been open about their struggles. Almost all of them fought those battles in public.

1. Aaron Carter

Aaron Carter
Aaron Carter | Credits: Entertainment Tonight

Aaron Carter spent most of his adult life fighting in front of an audience. The former teen star, who was also Nick Carter’s brother, was open about his addiction and mental health struggles, and the pattern was documented in real time on social media, sometimes by Carter himself.

On November 5, 2022, he was found submerged in the bathtub of his Lancaster, California, home. He was 34. The Los Angeles County coroner ruled the death accidental. The cause was drowning, with the effects of an inhaled aerosol gas and alprazolam listed as contributing factors (via TMZ).

2. Taylor Hawkins

Taylor Hawkins
Taylor Hawkins | Credits: Raph_PH, licensed under CCA 2.0, via Wikimedia Commons

Taylor Hawkins had survived this once already. In 2001, a heroin overdose in London left the Foo Fighters drummer in a coma for two weeks (via Rolling Stone). He spoke about it afterwards with unusual honesty and rebuilt his life around the band. Sadly, he was found dead in a Bogotá hotel room on March 25, 2022, hours before a scheduled festival performance.

Colombian authorities released a preliminary urine toxicology report listing ten substances, among them opioids, benzodiazepines, tricyclic antidepressants, and THC (via The Guardian). An official cause of death was never made public.

3. Adam Rich

Adam Rich
Adam Rich in Eight is Enough | Credits: ABC

Adam Rich was eight years old when America met him. However, his later years were filled with arrests, rehab stays, and relapses that he eventually stopped hiding. Months before his death, he posted that he had been sober for seven years and urged others not to give up. He died at his Los Angeles home on January 7, 2023, at 54.

The Los Angeles County Medical Examiner ruled the death accidental and listed the cause as the effects of fentanyl (via CBS News). His representative said afterwards that Rich had lived with a form of depression that resisted treatment, and had spent years trying to remove the stigma around discussing it.

4. Buddy Duress

Buddy Duress in a still from Flinch
Buddy Duress in a still from Flinch | Credits: Ardor Pictures

Buddy Duress never got to leave his past behind, partly because it became his career. Born Michael Stathis, he met Josh Safdie in 2013 after being released from jail on drug charges. He landed a role in Heaven Knows What, then went back to Rikers Island before the film even premiered.

In 2017, he told the New York Post, “No more drugs, no more partying.” He died in November 2023 at 38. The news only became public three months later, when his brother Christopher confirmed to PEOPLE that he died of “cardiac arrest from a drug cocktail.”

5. Liam Payne

Liam Payne in the music video of Strip That Down | Credits: Capitol/Republic
Liam Payne in the music video of Strip That Down | Credits: Capitol/Republic

Liam Payne had talked publicly about alcohol and addiction for years, including periods when the pressure of One Direction’s fame made it worse. He had been through treatment more than once. On October 16, 2024, he fell from a third-floor balcony at a hotel in Buenos Aires. He was just 31.

Argentine authorities determined the cause of death was multiple trauma and internal and external hemorrhage from the fall, and ruled out self-harm or third-party involvement. Final toxicology found traces of polydrug use. Investigators concluded he had not been fully conscious as he fell.

6. Angus Cloud

euphoria scene eerily predicted angus cloud death
Angus Cloud as Fezco in Euphoria | Credits: HBO

Angus Cloud was 25 and had been famous for four years. He played a drug dealer on Euphoria, a show built around addiction, which made what happened next truly sadder. A week after burying his father in Ireland, he died at the family home in Oakland on July 31, 2023.

The Alameda County Coroner ruled it an accidental overdose, caused by acute intoxication from the combined effects of methamphetamine, cocaine, fentanyl, and benzodiazepines (via NBC News). His mother Lisa later said she did not believe he intended to end his life, describing a son overwhelmed by grief.

7. Hayden Panettiere

Hayden Panettiere had written the book on her own struggle, literally. Her May 2026 memoir, This Is Me: A Reckoning, dealt openly with addiction, postpartum depression, domestic abuse, and the cost of growing up on camera. On August 16, 2026, she was found unresponsive at her home and pronounced dead at 36.

An autopsy found no trauma contributing to her death. Her official cause and manner of death remain pending toxicology results (via TMZ). Emergency dispatch audio referenced a possible overdose, though authorities have not confirmed one. The DEA has since joined the ongoing investigation.

8. Matthew Perry

Matthew Perry estimated he had spent millions trying to get sober, and his 2022 memoir laid out a life organized around opioids and alcohol while he was the funniest man on television. In his final months, he was receiving ketamine therapy for depression. He then began seeking unsupervised doses.

He was found dead in the hot tub at his Los Angeles home on October 28, 2023, at 54. The cause was the acute effects of ketamine, with drowning, coronary artery disease, and buprenorphine as contributing factors. Five people, including two doctors and his own assistant, have since been convicted and sentenced.

What are your thoughts on these substance abuse-related deaths? Let us know in the comments below!

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